Strong preclinical and clinical rationale supporting therapeutic efficacy

Cy Biopharma is leading the charge in developing a new class of small molecule therapies that address the root cause of chronic pain through central nervous system modulation.
Our mission is to deliver single-dose, durable treatments for pain conditions with few or no effective options, starting with rare and orphan indications where the need is urgent, and the impact is profound.
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Chronic pain, especially neuropathic pain syndromes, affects millions globally. These conditions often persist for years, severely diminishing quality of life. For many patients, today’s standard treatments fall short: expensive, invasive, short-lasting, or ineffective.
Despite the scale of the crisis, innovation has lagged. No FDA-approved therapies exist for some of the most debilitating forms of chronic pain. Cy Biopharma is here to change that.
We are the first company globally to develop a chronic pain therapy targeting the 5-HT2A serotonin receptor using a proprietary, naturally derived compound designed to reset maladaptive neural circuitry. Unlike conventional treatments, our lead program aims to interrupt the pain cycle at the neurological source, not just mask symptoms.
Strong preclinical and clinical rationale supporting therapeutic efficacy
Orphan drug strategy designed for regulatory acceleration and exclusivity
Non-invasive and easily scalable delivery method
Single-dose administration with long-term durability
Cy Biopharma
Why it matters?
We are advancing a treatment for a rare, underserved chronic pain disorder that causes severe post-traumatic pain with no approved therapies.
Our approach is positioned to meet Orphan Drug criteria, unlocking accelerated FDA pathways, market exclusivity, and potential reimbursement advantages.
Chronic pain is a multi-billion-dollar unmet medical need
Our lead indication represents a high-impact commercial opportunity
Our therapeutic approach may extend to a broad range of pain-related conditions
Backed by a world-class team of scientists, physicians, and biotech operators
Cy Team
Together, we bring decades of experience in bringing novel therapeutics to market, from discovery through regulatory approval.
CEO, serial entrepreneur and former CEO of neuroscience-based therapeutics company & Wall Street executive
CMO, former President of British Pain Society & current practicing physician at The London Clinic
COO, proven operational success in leading both FDA & EU drug product registrations
Patient advocate & Cy Biopharma Founder
Cy Biopharma
By investing now, you join us at a critical inflection point, with:
We are currently raising capital to fund our next clinical milestone. This round will support a proof-of-concept clinical trial for our lead program, with a clear roadmap toward a Phase 3 study.
A first-mover advantage
A highly de-risked clinical rationale
A well-defined path to market authorization
We’re not just developing drugs. We’re redefining what’s possible in pain medicine.